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The 12 best supplements for anxiety

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Which are the best supplements for anxiety? Especially now, it is normal that many of us worry, feel unease, experience fear, or panic. Research has suggested often that there are a lot of different supplements for anxiety such as vitamins, omega-3 fatty acids, and different herbal remedies that may help relieve the symptoms of anxiety.

Almost 7 million adults in the United States are dealing with anxiety and I'm sure the number is growing tremendously right now. But before running to the doctor and getting on medication (even though natural supplements for anxiety aren’t meant to replace prescribed medication or other doctor-approved therapies) I always encourage folks to try some of the best natural supplements for anxiety as well as herbal supplements for anxiety first. I found many of them very helpful and effective.

A list of the absolute best supplements for anxiety

What is the best supplement for anxiety and stress? Before diving deeper into the best supplements for anxiety have a closer look at your diet yourself. Are you lacking any nutrients? Sometimes when your diet is lacking key nutrients, dietary supplements may be the solution to symptom relief. In the meantime definitely try to get your diet back on track so you won't rely on the supplements for anxiety and stress for too long. Deficiencies can be identified by your doctor. Many of these supplements for anxiety I have tried myself so here's a list of the 12 best supplements for anxiety (plus the evidence supporting them):

1. Vitamin A

If you're suffering from anxiety you may need vitamin A which is an antioxidant that's been helpful as one of the best supplements for anxiety and stress. Take around 10,000 international units (IU) ( once-daily tablet). ▷ Buy on


I have tried GABA myself and it's one of the best supplements for anxiety. Have you ever heard of Gamma-aminobutyric acid (GAMMA)? It is an amino acid and neurotransmitter in the brain which when there's not enough GABA, your anxiety can get more severe. How much GABA should I take for anxiety? There hasn't been much research on it yet, but I ideal dose should range from 500 to 750 mg which can be split across multiple tablets of this anxiety supplement or taken as a once-daily tablet.▷ Buy on

3. Vitamin B-complex

As a group of 8 nutrients, B vitamins work strongly together in your body to manage different processes. One of them is your stress level. If your vitamin B is low a vitamin B-complex supplement can help to get you back on track with all the B vitamins that your body needs. In a study from 2017, it was found that people suffering from anxiety and depression had lower levels of vitamin B-12 in their blood. This is why vitamin B is one of the best supplements for anxiety. Check the label to find out how to dose your vitamin-B complex supplement for anxiety. This may vary from 300 mg to close to 500 mg. ▷ Buy on

4. L-theanine

L-theanine is also an amino acid and you can also find it in green tea. Looking at the chemical structure it is very similar to glutamate which is a naturally occurring amino acid in your body. Glutamate helps to transmit nerve impulses in your brain. L-Theanine appears to be similar to glutamate, which is why it is one of the best supplements for anxiety. Most capsules come as 200 mg dose. Start off with one per day and never exceed more than two per day. ▷Buy on

5. Vitamin C

Does vitamin C help anxiety? Taking vitamin C will prevent oxidative damage in your nervous system. This damage could increase anxiety so it's important to never lack vitamin C in your body. To take the most advantage of this supplement for anxiety take ranges from 500 to 1000 mg once a day. ▷Buy on

6. Vitamin D

Vitamin D is so important for you and one of the best supplements for anxiety because it supports your body to absorb other vitamins like calcium for example. Does Vitamin D make you happy? If you suffer from a vitamin D deficiency this can lead to other vitamin deficiencies and then affect your anxiety and make it worse. Your average supplement dose may range from 1,000 to 2,000 IU. I take my vitamin D once a day. ▷Buy on

7. Fish oil

Can fish oil help anxiety? As we know fish oil is high in omega-3 fatty acids, which are antioxidants. These Omega-3 supplements like EPA and DHA have been helping reduce anxiety. But how much fish oil should I take for anxiety? Make sure to take a combined dose of EPA, ALA, and DHA of 2.000 mg once a day. ▷Buy on

8. Magnesium

Magnesium is essential for our health and our body doesn't even need so much of it. As one of the best supplements for anxiety and stress making sure you're never lacking magnesium will help to get rid of anxiety symptoms. Actually, magnesium is necessary for the proper functioning of almost every system in your body which makes this anxiety supplement even more crucial. How much magnesium should I take for anxiety? I take my magnesium first thing in the morning on an empty stomach (500 mg). ▷Buy on

9. Vitamin E

When you're stressed and anxious, your body uses a lot of vitamin E (another antioxidant). For the ideal balance and to reduce symptoms of anxiety, a vitamin E supplement will help. It will ease stress and reduce oxidative stress. Around 200 mg is the ideal dose for this anxiety supplement. ▷Buy on

What is the best natural supplement for anxiety?

If you're now wondering how can I treat anxiety naturally, there are actually many ways to treat anxiety with herbal supplements as well. Again, talking to your doctor before is highly recommended to find out if there are any deficiencies that may cause your symptoms. There are certain herbs that contain phytochemicals that may support your body to ease symptoms associated with anxiety. Do natural supplements work for anxiety? Yes, and these are my 3 favorites when it comes to natural supplements for anxiety.

11. Lavender

Lavender is famous for being a soothing stress remedy. People use it also to relax before going to sleep. Me personally, I also love the smell of lavender which makes it one of my favorite natural anxiety supplements. How do you use lavender oil for anxiety? I've been using a diffuser in my apartment where I mix the essential oil with water. But you can also take lavender tablets and the average supplement dose is around 400 mg. ▷Buy on

12. Ashwagandha

Some say Ashwagandha (adaptogen and Ayurvedic remedy) is just as effective as certain medications in reducing anxiety. This one I haven't tried myself but my close friend is using it for years now while dealing with her anxiety. She also mentioned her serum cortisol levels were substantially reduced when taking this supplement for anxiety. Take 900 mg of Ashwagandha split in two times per day.▷Buy on

13. Passionflower

You most likely know this one for its sweet passion fruit. But passionflower (Passiflora incarnata) is also a great remedy for anxiety and the last recommendation on my list of anxiety supplements. A supplement (500 mg) or tincture of the flowers has worked best for me.▷Buy on

Also, note these natural supplements for anxiety and stress

The list of natural supplements for anxiety is long. There are a few more that I heard good things about in being very helpful in fighting anxiety long term.
  • Bacopa
  • Chamomile
  • Kava kava
  • Rhodiola.

Where to buy the best supplements for anxiety and stress?

After doing your research and consulting with your doctor you can go ahead and buy your anxiety supplements online. Oftentimes, it is much cheaper to buy them on Amazon for instance than getting them from your local pharmacy.

Final thoughts on the best anxiety supplements

As I mentioned at the beginning of this article, give these anxiety supplements a try before going on medication from your doctor. The side effects are oftentimes not worth it and natural anxiety supplements are always worth a shot. ▷ Also, consider meditation, yoga, deep breathing techniques, and exercising in general to manage your symptoms.
Why you can trust Sabrina Wieser
Runningbrina is committed to bringing you unbiased ratings and information. Her editorial content is not influenced by advertisers. Sabrina uses data-driven methodologies to evaluate all products, so all brands are measured equally.
  • Most featured running blog, past 6 years
  • USATF certified running coach
  • Experienced endurance athlete
  • 7 marathons

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